DSIP (DELTA SLEEP INDUCING PEPTIDE)

WHAT IS DSIP?
Delta Sleep-Inducing Peptide (DSIP) is a well-known neuromodulator and natural sleep-promoting nonapeptide with many other physiological functions. It is typically found in the brain and easily passes the blood-brain barrier. It has been discovered and heavily studied for over 40 years.

DSIP has been used for the treatment of poor sleep, pain conditions, stress-related symptoms, low testosterone (via stimulation of LH), and even sometimes as an antioxidant and anti-cancer protein. It exhibits a pronounced stress-protective action and decreases stress-induced metabolic and functional disorders in both humans and animals exposed to a variety of stresses. Research has also shown it can improve hormone levels and physical performance.

BENEFITS OF DSIP:

• Can restore disturbed sleep patterns
• Can promote LH and GH release
• Can reduce persistent/chronic pain
• Can modulate cortisol production

Sleep:

DSIP is considered a sleep-promoting substance rather than a sedative. It modulates sleep and wake functions, with greater activity in circumstances where sleep is disturbed. Unlike many sleep aids, DSIP does not disrupt sleep cycles. There are five stages of sleep, broken down into REM (Rapid Eye Movement) and NREM (Non-Rapid Eye Movement) stages. These stages are vital for physiological processes and hormone production. DSIP helps improve the ability to fall asleep and promotes more restful sleep without affecting these important stages.

Hormones:

DSIP plays a key role in neuroendocrine regulation and the release of anterior pituitary hormones. It influences the secretion of adrenocorticotropic hormone (ACTH), luteinizing hormone (LH), and growth hormone (GH), and is involved in regulating circadian rhythms. Administration of DSIP has been shown to enhance hormone production and regulation, increasing LH and GH production while decreasing somatostatin. This results in improved production of desirable hormones (LH, GH) and reduced production of undesirable ones (cortisol and somatostatin).

Research:

Gimble JM, Ptitsyn AA, Goh BC, Hebert T, Yu G, Wu X, Zvonic S, Shi X-M, Floyd ZE (2009). “Delta sleep-inducing peptide and glucocorticoid-induced leucine zipper: potential links between circadian mechanisms and obesity?”. Obesity reviews 10: 46–51.
Kovalzon VM (1994). “DSIP: a sleep peptide or unknown hypothalamic hormone?”. J. Evol. Biochem. Physiol. 30: 195–199.
Pollard BJ and Pomfrett CJD (2001). “Delta sleep-inducing peptide”. Eur. J. Anaesthesiol. 18: 419–422.
Steiger A and Holsboer F (1997). “Neuropeptides and human sleep”. Sleep 20: 1038–1052.

*** Please note: All injectables come with the required amount of sharps and swabs necessary for the duration of your treatment plan. If you’re purchasing a vial, we recommend purchasing a sharps box for safe disposal. ***