Nicotinamide Adenine Dinucleotide 100mg/ml x 10ml
What is NAD?
NAD, or Nicotinamide Adenine Dinucleotide, is a crucial molecule in cellular metabolism. Without NAD+, the body would cease to function in just 30 seconds. It not only helps convert food into energy, but it also plays a vital role in maintaining DNA integrity and supporting the body’s defense mechanisms against aging and disease.
What does NAD do in the body?
NAD+ acts as an electron shuttle, transferring electrons between molecules. It is essential in metabolic reactions that generate adenosine triphosphate (ATP), the body’s primary energy molecule. Without sufficient NAD+, ATP production is inhibited, affecting cellular energy. NAD+ also regulates the sleep/wake cycle, supports DNA repair, and helps manage the body’s metabolic functions.
Reductions in NAD levels with aging
As we age, NAD+ levels naturally decline, which may contribute to various age-related diseases. DNA damage activates the enzyme PARP, which uses NAD+ for DNA repair, leading to NAD+ depletion. This depletion, along with other factors like immune system enzyme activation, accelerates aging and metabolic disorders.
How is NAD made?
NAD+ is synthesized in the body via two pathways: the de novo pathway, which uses the amino acid tryptophan, and the salvage pathway, which uses vitamins like nicotinamide and nicotinic acid. These pathways convert these precursors into NAD+, supporting the body’s energy and repair processes.
NAD+ Precursor Supplementation
Supplementing with NAD+ precursors like nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) is a promising strategy to boost NAD+ levels and combat aging. Although studies in animals show potential benefits, further clinical trials in humans are necessary to confirm their effects.
Potential Benefits of NAD+
NAD+ is essential for mitochondrial function, gene regulation, and cellular repair. As NAD+ declines with age, replenishing it could help counteract age-related diseases, enhance lifespan, and improve overall health.
Aging and Muscle Function
NAD+ is vital for maintaining healthy mitochondrial function, which in turn supports physical performance. Increasing NAD+ levels in muscles has been shown to improve exercise capacity and mitochondrial health in animals, suggesting potential benefits for humans as well.
Metabolic Disorders and NAD+
Reduced NAD+ levels are linked to metabolic disorders, including obesity and diabetes. Supplementing with NAD+ boosters has shown promise in alleviating symptoms of these conditions in animal studies, providing hope for future therapeutic applications.
Does NAD increase lifespan?
In animal studies, boosting NAD+ levels has been shown to modestly extend lifespan and provide protection against age-related diseases. However, the translation of these results to humans is still under investigation, with clinical trials ongoing.
How to Boost NAD+ Levels
Increasing NAD+ levels can be achieved through exercise, fasting, and supplementation with NAD+ precursors like NMN and NR. These lifestyle changes and supplements help stimulate NAD+ biosynthesis, supporting energy production, DNA repair, and overall health.
The Future of NAD+
As the global population ages, the need for solutions to age-related diseases becomes more pressing. NAD+ has shown potential in treating conditions like heart disease, diabetes, and Alzheimer’s in animal models. Ongoing research aims to determine how these findings can be applied to human health and aging.
*** Please note: All injectables come with the necessary sharps and swabs for your treatment plan. If purchasing a vial, we recommend a sharps box for safe disposal. ***







